BSC 310 Lecture Notes - Lecture 82: Guanosine Pentaphosphate, Heat Shock Protein, Non-Coding Rna
20 Mar 2019
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Other global control networks: global networks include activators, repressors, signal molecules, two-component regulatory systems, regulatory rna, and alternative sigma factors. In e. coli, the heat shock response is controlled by alternative sigma factors that are not readily degraded under elevated temperatures so they persist and allow some genes to be more highly expressed under high heat conditions. ; time when catalytic rna was thought to be the only self-replicating life form. If tryptophan is plentiful, there will be enough charged tryptophan trnas and the leader peptide will be synthesized, resulting in termination of transcription for the remainder of the operon. If tryptophan is scarce, the leader peptide will not be synthesized and the remainder of the operon will be transcribed. Regulation of enzymes and other proteins: focus on controlling the activity of enzymes already present in the cell, two major processes, feedback inhibition, post-translational regulation. Isoenzymes: some feedback inhibition pathways use isoenzymes.
