BSC 422 Lecture Notes - Lecture 5: Gleason Grading System, Prostate Cancer, Testicular Cancer
1 Feb 2018
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Gleason score based on how much the cancer looks like healthy tissue when viewed under a microscope. Pathologist looks at how the cancer cells are arranged in the prostate and assigns a score on a scale of 1-5. Cancer cells that look similar to healthy cells receive a low score. Cancer cells that look more aggressive receive a higher score. To assign the numbers, the doctor determines the main pattern of cell growth, which is the area where the cancer is most obvious; looks for any other less common pattern of growth; and gives each one a score. The scores are added together to come up with an overall score between 2 and 10. Lowest score used is 6 low grade cancer. 8, 9 or 10 high grade cancer. Gleason x: the gleason score cannot be determined. Gleason 6 or lower: the cells are well differentiated, meaning they look similar to healthy cells.
