BSC 444 Lecture Notes - Lecture 2: Rna Virus, Symmetry, Reassortment
6 Sep 2017
School
Department
Course
Professor
Document Summary
Potential virus parts: genome, capsid, knobs, projections and fibers, tails, envelopes and internal membranes, occlusion bodies, rna in dna viruses, cell molecules, every virus has minimum genome and capsid. Viral genome size: maximum size is determined by constraints that vary within each genome category, constraints are least severe for dsdna genomes. Secondary and tertiary genome structure: ss polynucleotide chains can form secondary and tertiary structures through weak bonding patterns, shape gives function, dnas serve as enzymes. Involved in regulatory functions, ribosome interacts with 5" cap. Viral genome repeat sequences: repeats contain, promoters, enhancers, origins of replication, types, terminal (dtrs and itrs, internal (dirs and iirs) Capsid structures: functions- protect the genome from one cell to another or one person to another, these particular shapes have round edges, strongest shapes to get through repulsive forces, force is evenly spread out over entire face. Helical symmetry: subunit- identical protein molecules folded up into its tertiary structure in the exact same way.
