CH 461 Lecture Notes - Lecture 32: Serum Albumin, Basal Metabolic Rate, Myocyte

12 views2 pages

silvercicada472

12 Jul 2018

School

University of Alabama

Department

Course

CH 461

Professor

Dunkel

For unlimited access to Class Notes, a Class+ subscription is required.

Document Summary

A large number of reactions go on at the same time and remembering how they fit together with any kind of logic is difficult. The temptation to simply memorize the individual reactions is great, but some underlying principles can help your understanding. Glucose is a preferred source of metabolic energy in almost all tissues. Glucose can be metabolized either aerobically or anaerobically. Although more energy is available by oxidative metabolism, some tissues can use glycolysis for a rapid burst of energy. The sources of glucose vary in different tissues. Muscle is the largest consumer of glucose during exercise and can get glucose either from the circulation or by breaking down internal glycogen reserves. Two types of skeletal muscle exist and are distinguished by their physiological properties and their glucose metabolism. The relative lack of mitochondria in these fibers causes the white appearance. The rapid breakdown of glucose by anaerobic metabolism means that atp is made rapidly.

Related Questions

1. C6H12O6 + 6O2 Ã 6CO2 + 6H2O Glucose is being _____ to _____ and oxygen is being _____ to _____. a. oxidized; carbon dioxide; reduced; water b. oxidized; water; reduced; carbon dioxide Incorrect c. reduced; water; oxidized; carbon dioxide d. reduced; carbon dioxide; oxidized; water

2. Which of the following stages in the breakdown of the piece of toast you had for breakfast generates the most ATP? a. the citric acid cycle Incorrect b. glycolysis c. the digestion of starch to glucose d. oxidative phosphorylation

3. Which of the following is a catabolic pathway? a. gluconeogenesis b. production of starch Incorrect c. glycolysis d. production of glycogen

4. Per molecule, the oxidation of a fatty acid results in _____ energy storage than the oxidation of glucose. a. the same b. less Incorrect c. more d. None of the above; fatty acids cannot be oxidized.

5. Of the eight reactions in the citric acid cycle, how many are oxidation-reduction reactions? a. one b. two c. three d. four e. five

6. The process of glycolysis transfers the energy in sugar molecules into the stored energy of activated carriers such as ATP and NADH. Which statement is true about glycolysis? a. Only eukaryotic organisms do glycolysis. b. The ten reactions of glycolysis are identical in all eukaryotic cells, but are different in prokaryotic cells due to their diverse metabolic strategies. Incorrect c. The ten reactions of glycolysis are identical in almost all living organisms on the planet. d. There are many ways to oxidize glucose and transfer energy into activated carriers; the diversity of organisms on the planet is reflected in the diversity of their mechanisms of glycolysis.

7. Referring to the sentence completed in #13 above, the purpose of the latter reaction (in active muscle cells) is to _____. a. accumulate lactic acid in the cell, which provides additional energy for the production of ATP Incorrect b. slow down glycolysis until oxygen becomes available again c. accelerate the Krebs cycle, which will restore the oxygen supply d. regenerate NAD+ so that glycolysis can continue in the absence of oxygen

8. What are the products of the citric acid cycle? a. carbon dioxide, NADH, FADH2 and GTP b. carbon dioxide, NAD+, FAD and GTP c. NADH, FADH2, and acetyl CoA Incorrect d. carbon dioxide and water

9. Which statement is true about enzymes? a. Enzymes catalyze chemical reactions because they make inherently endergonic reactions exergonic. b. Each enzyme in a cell can catalyze many different chemical reactions involving chemically different substrates. Incorrect c. Enzymes can only catalyze reactions in one direction. d. After catalyzing a reaction, an enzyme is permanently altered and can no longer bind substrate. e. None of the above is true. 1

10. âG measures the change in free energy in a system as it converts reactant (Y) into product (X). When [X] = [Y], âG is equal to _____. a. RT b. ÎGÂ° + RT c. ÎGÂ° d. ln [X]/[Y]

11. The âGÂ° for the hydrolysis of ATP is -7.3 kcal/mol. What conditions in the cell would lead to a âG for ATP hydrolysis of -11 kcal/mol? a. An increase in the ATP/ADP ratio b. An increase in anabolic activity in the cell c. Transport of ATP out of the compartment where the reaction is occurring Incorrect d. A decrease in the ATP/ADP ratio

12. In the first reaction of glycolysis, a phosphate transferred from ATP to a glucose molecule to produce glucose-6-phosphate and ADP. Under conditions existing in the cell, the free energy change for this reaction is -8.0 kcal/mole. Which of the following statements is true? Recall that the âGÂ° for the hydrolysis of ATP is -7.3 kcal/mol. a. Glucose concentrations in the cell are always low, making this reaction more favorable than would be expected. b. This reaction is less favorable than would be expected, given the âGÂ° of ATP hydrolysis. c. Glucose-6-P concentrations in the cell are very low relative to glucose concentrations, making the reaction more favorable than would be expected. d. The âGÂ° for the addition of a phosphate to glucose must be -0.7 kcal/mole.

13. Protein E can bind to two different proteins, S and I. The binding reactions are described by the following equations and values: E + S --> ES Keq for ES = 10 E + I> EI Keq for EI = 2 Given the equilibrium constant values, which one of the following statements is true? a. When S is present in excess, no I molecules will bind to E. b. E binds I more tightly than S. c. The binding energy of the ES interaction is greater than that of the EI interaction. d. Changing an amino acid on the binding surface of I from a basic amino acid to an acidic one will probably make the free energy of association with E more negative.

Exercise Pharmacology

Chapter 1

1. Distinguish between pharmacokinetics, pharmacodynamics, and pharmacology.

2. How would you determine a drugâs doseâresponse curve?

3. What is meant by drug efï¬cacy? Potency?

4. How would you determine equipotent doses for two drugs of the same class?

5. What features of a drugâs action may make its pharmacokinetic properties more sensitive to exercise?

6. How might a drugâs volume of distribution be altered in the case of a person who is obese? A person who is elderly?

7. How might you explain an antagonist with partial agonist activity?

8. What are some of the ways that taking a second drug can affect the activity of the ï¬rst drugâor either drug?

Chapter 2

1. Bill is 60 years old and in reasonable shape. Working out on an elliptical machine, Bill sees that his heart rate is 135 bpm. Can you determine his ap-proximate exercise intensity without hooking him to a metabolic cart? What is he primarily burning for energy?

2. Your mother asks your advice about starting an exercise program. She is in pretty good health, but wants to drop some weight besides improving her cardiovascular health. What kind of exercise plan would you recommend to get her started? How would you explain to her the beneï¬ts of such a plan? After the initial couple of weeks, would you recommend any changes that might help her with her long-term ï¬tness goals?

3. Compare and contrast the three major muscle ï¬ber types in terms of their metabolism and fuel preference.

4. You are a graduate student working in an exercise physiology lab. You see a claim in a bodybuilding magazine about a supplement that rapidly increases power, strength, and muscle mass. How would you set up an experiment to test whether these claims are true?

5. Obesity is now considered by some to be reaching epidemic proportions. What is contributing to this trend, and what can be done?

Chapter 3

1. Compare and contrast the sympathetic and parasympathetic nervous systems.

2. What is meant by allostatic load, and how does it differ from stressing over a single test?

3. Explain three ways drugs can affect the signals transmitted by nerve cells.

4. How might exercise lessen the effects of stress?

5. Describe some of the theories that attempt to explain the bodyâs paradoxical response to exercise.

6. What are the key physiological changes that occur during the ï¬ght or ï¬ight response? How do they help in survival?

Chapter 4

1. What is meant by âbeta-blockers with ISAâ? What advantages might these drugs have? Disadvantages?

2. What property makes some beta-blockers cardio selective?

3. What are the effects of beta-blockers on exercise physiology?

4. A serious walker (5 miles/day) notices that she has stopped losing weight since starting her new prescription of propranolol (non-cardio selective, without ISA). She also fatigues more quickly than she used to. What can you offer her as an explanation?

5. The NCAA and USOC have banned beta-blockers from many types of com-petition. Why?

Chapter 5

1. Bill, a deconditioned, recently divorced 50-something exec driving that new BMW, wants to drop some weight and look good. He has high blood pressure. What kind of exercise regime would you recommend?

2. Why do calcium channel blockers mostly affect smooth muscle, with little effect on skeletal muscle?

3. How do calcium channel blockers reduce blood pressure?

4. Mary enjoys running and likes to compete in 10K races and half marathons. She also is diagnosed with high blood pressure. What are her options for regulating her blood pressure while maintaining a training schedule and remaining competitive?

5. How do ACE inhibitors affect blood pressure?

6. How do ARBs affect blood pressure?

brownalpaca148

CH 461 Lecture Notes - Lecture 32: Serum Albumin, Basal Metabolic Rate, Myocyte

Document Summary

Get access

Related Documents

11:067:330 Lecture Notes - Lecture 10: Acetyl-Coa, Adipose Tissue, Skeletal Muscle

NUTR 3210 Lecture Notes - Lecture 8: Branched-Chain Amino Acid, Myocyte, Urea Cycle

NUTR 3210 Lecture Notes - Lecture 8: Vo2 Max, Acetyl-Coa, Alanine

Related Questions