BIO 200LLB Lecture Notes - Lecture 15: Aneuploidy, Polyploid, Down Syndrome

• School: University at Buffalo
• Department: Biological Sciences
• Course: BIO 200LLB
• Professor: Herreid, C F

Document Summary

Abrupt changes in the genetic material occurring typically during cell division. A. loss or duplication of whole chunks of dna. Large pieces of chromosome moved to another place in the. Small pieces of dna shifting within the genome. Sperm parent cells divide every 15 days. This continuous division and copying of dna lead to errors & the rate of error. A 20 year old man will have an average of 25 new point mutations in his sperm. A 40 year old man will have 65. A 40 year old woman will have 15 increases significantly with age. Men have a much higher rate of mutation than women. Val asp pro pro phe (pr (aa)) When the dna changes, then the mrna changes and then that can make the protein outcome change. Cat tta tgg agg aaa a (dna) Leads to short extra long non-functional proteins.