BSCI 105 Lecture 26: Translation and Mutation AND Lecture 27: Introduction to Gene Expression
30 Nov 2016
School
Department
Course
Professor
Document Summary
Small and large: mrna binds to small section, small and large sections are bound together using gtp, large unit has 3 sections. A trna bonds to: mrna codon read from 5" to 3". 3" to 5" trna and amino acid held together with ester bond. Any change in the genetic material of a cell or virus. If a mutation is not corrected it can be inherited by subsequent generations. This may result in heredity diseases including inborn errors of metabolism. Mutation may be as small as one base pair or as large as thousands of base pairs. The effects of a single base pair change range from none (silent mutation) to catastrophic: outline. Point mutations: changes in a single base pair. Missense mutation: results in a change in one amino acid in the gene product (protein) Silent mutations: have no effect on protein function. Nonsense mutations: introduce a stop codon that causes translation to terminate prematurely.
