BSCI 223 Lecture Notes - Lecture 20: Pneumocystis Jirovecii, Virulence Factor, Indoor Air Quality
Document Summary
16% (920,136) of deaths of children under 5. Etiologic agents: streptococcus pneumoniae, haemophilus influenzae type b, respiratory syncytial virus (rsv, pneumocystis jiroveci (hiv infection) Prevention: vaccination (hib, pneumococcal, measles, pertussis, reduction of indoor air pollution, breast feeding. Will transfer ability to fight the virus. Pathogenicity: ability of a microorganism to cause disease. Virulence: virulence factors contribute to virulence (these are all phenotypes they derive from the genotype) Toxins: chemicals that harm tissues or trigger host immune responses that cause damage: toxin itself can cause damage or will cause a response that causes damage cells. Two types or no longer part of the cells when they are active. Toxemia: presence of toxins in the bloodstream. The toxins are carried beyond the site of infection they are often excreted: exotoxins often proteins or short peptides that are excreted out of, endotoxins . Present in gram negative and gram positive. Only present after the bacteria cells were lysed.