BSCI 223 Lecture Notes - Lecture 22: Chemokine, Cell-Mediated Immunity, Gram-Positive Bacteria
26 Apr 2016
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Bacteria may be innately resistant to antibiotic (spectrum of antibiotic action) Bacteria can acquire antibiotic resistances: acquire genes that code for phenotype: antibiotic resistance. Symptoms caused by virus: viruses are not susceptible to antibiotics: knocking down some microbiota, and can develop resistance, no bacteria are involved. Transitioning from innate immune response to adaptive immune response. Chemotaxin recruiting a neutrophil from blood- example of chemokine. 103 f body temperature- fever- pyrogen causing whole body to heat up. Opsonization (making foreign object edible for the phagocytotic cell) by c3 component of complement. Lysozyme (inherent to body) in tears degrading pg cell wall: lysozymes work on both gram negative and gram positive, but work best on gram postitive- need to get through the cell wall. Edema (come along with fluid, which leads to swelling) at site of infection leading to swelling. Specific host defenses: layer 3 -(adaptive: learns by experience) Not immediate: requires proliferation of specific response cells.
