KNES 360 Lecture Notes - Lecture 17: Diffusing Capacity, Haemodynamic Response, Chronic Obstructive Pulmonary Disease
31 Oct 2017
School
Department
Course
Professor
Document Summary
Diffusing capacity of lung from rest to exercise increases significantly. Diffusing capacity of lung from rest to exercise with copd- depends on the severity of the disease, not the same as a normal. The bulk of copd are people with emphysema (lower dcl because damage to alveoli) and chronic bronchitis (inflammation on bronchioles, so they constrict and reduces the amount of air that can be ventilated) When we look at pulmonary blood flow (pbf) is about the same as resting co about 5-6. Matching of co and pbf 1 to 1 ratio. If major portion of zones aren"t perfused, then this leads to the reduction of diffusing capacity: emphazema problem at respiratory membrane and gas exchange, chronic bronchitis won"t allow the air in. Same for resting diffusing capacity (like co)- not much different at low intensity exercise, will be similar.
