KNES 360 Lecture Notes - Lecture 2: Diffusing Capacity, Perfusion, Chronic Obstructive Pulmonary Disease

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Normal across membrane for healthy: exercise response: increase in capacity. Blood volume does not change from rest to exercise. Cardiac output and pulmonary blood flow occur at about the same rate: 5-6 liters blood/ min. Increase in pulmonary blood pressure: rest -exercise, lung become more fully perfused, greater diffusion and blood flow in zones 1 and 2 instead of just down in 3. Increase in the diffusing capacity of the lung. Increase in pulmonary blood flow: q=5-6, will have similar blood flow. Increase !, increase in bp lung is more fully perfused, greated diffusion of oxygen across membrane. Increasing diffusion capacity to allow more blood oxygen in body: low exercise capacity. Increased cardiac output during maximal exercise: greater blood volume, greater capcity to increase blood blow in the lungs, more perfused=increased diffusing capcity. Put on exercise program, what would happen: measured pulmonary blood flow= capacity will improve with training. Moderate to se(cid:448)ere: do(cid:374)"t sho(cid:449) (cid:373)u(cid:272)h of a(cid:374) adaptatio(cid:374)

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