PSYC 406 Lecture Notes - Lecture 3: Hebbian Theory, Nmda Receptor, Synaptic Plasticity
7 Dec 2016
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Spatial navigation in rats ii starting at 2:205/5/2016 8:18:00 pm. Explains some types of associative learning in which simultaneous activation of cells leads to pronounced increases in synaptic strength. Can create a lot more input into b and thus might let it go to threshold. Ltp is the ca1 region of the hippocampus is induced by high frequency stimulation (tetanus) to an input pathway: put a stimulating electrode in schaffer collaterals (near projections) can bring them to threshold and have them fire. Record from ca1 region pyramidal cells: now in order to get ltp have to stimulate them strongly high frequency stimulus region (tetanus) ~ 40hertz (40 times per second. --> inorder to observe ltp in post synaptic cell. Post synaptic facilitation: have a second pathway you don"t stimulate and you look at what happens when you tentanize one pathway and not the other. To make sure there is no global effect,(control: very rapidly increases- pathway one for tetanus still at.
