BIL 150 Lecture Notes - Lecture 11: Ependyma, Dynein, Motor Protein

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Dynein: the motor protein for cilia, flagella. Motor protein moves microtubules in cilia and flagella. Kinesin: walk to positive end of microtubules. Prevents bending of microtubules so dynein movement causes cilia to bend. Ependymal cells: in brain, wave their cilia. Cell movement is related to the cytoskeletal framework/ability to change shape/move. Built with tension and compression opposing each other. Ex: muscle cell (actin filaments, myosin filament, myosin arm) Myosin has globular head: a motor protein (like kinesin, dynein. Motor proteins can change their conformation and move along microtubules. Movement due to rearrangement in cell architecture. Actin/myosin interactions= circular flow of cytoplasm around cell. Actin filaments respond to pressure by forming branches at curvies spots to resist pressure. Ex: motor proteins (like kinesin) in cell transport. Connections between cells in a multicellular organism. Most common in epithelial cells of animals (ex: intestines) Each junction has protein in membrane that signal another specific protein in in another membrane.

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