KIN 232 Lecture Notes - Lecture 18: Carbonic Anhydrase, Antigen, Microcytic Anemia
Document Summary
Pluripotent hematopoietic stem cell proerythroblast reticulocyte erythrocytes. Difference in aerobic capacity between men and women vo2. Men have more blood volume, more hb so. Carbonic anhydrase co2 combines with h2o and turns it into bicarbonate. *rbcs produced in long bones, sternum, rib, and vertebrae in children, and the thorax becomes more active in adults. Tissue oxygenation erythropoietin from kidneys stem cells proerythrocytes reticulocytes erythrocytes reticulocyte 1% of rbc volume; baby rbc, has mitochondria. If there is a low count, indicates marrow and kidneys isn"t producing. Function mass of rbcs tightly regulated: oxygenation of tissue, maintenance of q. Ischemia: an inadequate blood supply to an organ or part of the body, esp. heart. Epo (erythropoietin): hormone produced in kidneys that promotes formation of rbc by bone marrow: epo is used as treatment for anemia, epo released from min-hrs and peaks at 24 hours. Rbcs appear ~ 5 days later: live at high altitude, train at low altitude produce more blood cells.
