HSC 4551 Lecture Notes - Lecture 8: Kidney Failure, Jaundice, Glycogen

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Maroon-colored organ occupies the right upper quadrant of the abdomen underneath the diaphragm. Only organ with a double blood supply. Receives about 30% of oxygenated blood from the hepatic artery. Receives 70% of the blood from the portal circulation. Venous blood from the stomach, intestines, pancreas, and spleen and carried by the portal vein to the liver. Right and left lobe divided by the falciform ligament. Bile is carried by the right and left hepatic ducts. Joins with the cystic duct from the gallbladder to form the common bile duct. Combines with the pancreatic dust to empty into the duodenum. Metabolism of free fatty acids and glucose. Made up of numerous tiny hexagonal-type units called lobules that surround a central vein. Liver cells, called hepatocytes, form plates that radiate out from the central vein as a spoke of each wheel. Each spoke is made up of one to two layers of hepatocytes.

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