PHC 3302 Lecture Notes - Lecture 4: Aum Shinrikyo, Botulinum Toxin, 2001 Anthrax Attacks
Document Summary
Japanese scientists dropped bags of fleas infected with plague over certain. Chinese provinces: cult followers of the indian guru bagwan shree rajneesh laced several area restaurant salad bars with salmonella, 750 cases, no fatalities, 1990s. Lesser ease of dissemination/transmission and lower morbidity/mortality rates: category c. Incubuation period: 2-43 days, possibly longer, median for 1st 10 bioterrorism related cases was 4 days, with a range of 4-6 days, mode of infection. Macrophages ingest the spores, but only some are destroyed. Surviving spores enter the regional lymph node, where they germinate at various times: mortality rate, 45-97, with antibiotics, 75, death can occur within hours of onset, gastrointestinal, oropharangeal, gastrointestinal. Incubation: 1-7 days, but typically 2-4 days, manifestation, ulcerations within oral cavity, esophague, and/or gi tract. Intitial therapy for meningeal, inhalation, or gastrointestinal anthrax. Less than 10 in the u. s: most occurring in the west/southwest of the u. s, primary forms of plague, bubonic.
