BIS 101 Lecture Notes - Lecture 14: Telomere, Genome Size, Noncoding Dna
16 Dec 2017
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What does a genome size mean? more dna more complexity. More genes evidence said that this is not true. Coc redundant = same fxn evolutionary important: protect from mutation facilitated evolution: example. Hemoglobin fetal genes hemoglobin old copy adult genes. Hemoglobin went from a combined fxn to a split fxn: repetitive dna. We don"t know: dispersed repeats (a bit bigger repeats, nobody knows how it"s made; how it"s copied, 50-500 bp repeats, fewer copies in the genome < 100, no specific replication mechanism. No orf (actually a bunch of stop codons) No promoter, doesn"t get transcribed: transposons, dna elements > 1kb, contain replication and movement machinery we can recognize (polymerases, etc. , called dead viruses . Most papers on 1-100 genes (10% of the genes) about 90% are not studied less information on them harder to study. When use functional genomics you do thye following: find all protein genes and rna. Compare to what is known: mutant library.
