NPB 113 Lecture Notes - Lecture 14: Atrioventricular Node, Pacemaker Potential, Stroke Volume

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Sns and pns input to pacemaker at sa node , to the conductive pathways , and av node. T rate of ap conduction through conductive pathways. " ts ns and i pns input to sa node ( primary pacemaker ) Hcn channel : ne bl has to receptor on hcn. " leads to t if ( nat current ) to t rate of depolarization. L - type cart channel : ti ca - l during phase o. T cast influx leads to t rate of depolarization. In av node ( n - region ) : ap conducted faster em time snoaiiiiamsns activity l l shorter. T ap conduction velocity only i pacemaker potential. - - - - - - - . - - - - threshold. Ach binds to muscarinic receptor to protein coupled ) Contribute to slower depolarization to threshold vascular function curve. Mean systemic ( venous ) filling pressure -

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