BIO SCI 38 Lecture Notes - Lecture 12: Dentate Gyrus, Purkinje Cell, Pyramidal Cell

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10 Jan 2020
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Pyramidal neurons (hippocampus, neocortex), medium spiny neurons (striatum), granule cells (dentate gyrus), interneurons, purkinje cells (cerebellum), etc. The pattern of genes that cell expresses. The functional unit of dna that contains the elements needed to control the expression of, and information needed to make a protein. The standard dogma of biology, part 1. Transcription (dna to rna) take place in the nucleus. Rna is processed to messenger rna (mrna) in the nucleus. Translation (rna to protein) takes place in the cytoplasm (cell body or dendrites) Proteins are the workhorses of the cell, orchestrating many of the main cellular processes. The standard dogma of biology, part ii. A protein"s function is dictated by its conformation (shape), which is determined by the primary (linear) sequence of its amino acids. Mutations of single amino acids can therefore disrupt the function of a protein.