BIO SCI 38 Lecture Notes - Lecture 9: Locus Coeruleus, Nucleus Basalis Of Meynert, Raphe Nuclei
10 Jan 2020
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Document Summary
Generated in glycolysis and the krebs cycle from fuels such as glucose by a host of enzymes. Oxygen is needed during the krebs cycle for the conversion of fuels to atp. Used in cellular processes of growth, maintenance, and communication. Brain= ~2% of mass of human body. Brain requires ongoing blood flow to provide oxygen to power the brain"s workings. Action potential firing uses lots of atp. Neurons have the most exquisite structure of cells in the body, which allows compartmentalization of function and directionality of information flow in the brain. Neurons are not directly connected to one another, but are very close. Synaptic cleft is ~ 20 nanometers ave. human hair is 70,000 nanometers. Gaba (gamma aminobutyric acid) is the major inhibitory neurotransmitter. When gaba is released and binds gaba receptors, a channel opens and lets negatively charge chloride ions (cl-) inside to hyperpolarize the neuron.
