BIO SCI 38 Lecture Notes - Lecture 22: Fear Conditioning, Rodent
10 Jan 2020
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Drugs that disrupt or facilitate specific cellular processes can be given during this consolidation period to impair or enhance memory at testing, respectively. This consolidation window is fairly narrow, and generally seen in only the first hour or two after training. The interpretation of ecs experiments was controversial. The possibility that ecs produces amnesia because it produces a retrieval. Some behavioral test methods for studying memory: failure could not be ruled out. With weak shock, performance is near the floor , making it difficult to see a memory impairment. With strong shock, performance is near maximal, making it difficult to see a memory enhancing effect. Researchers manipulate the strength of shock in ia training to detect manipulations impairing or enhancing memory. In fear conditioning, after the rat has explored the conditioning context, an auditory cue (tone) is presented for about 15 seconds.
