BIO SCI 45 Lecture Notes - Lecture 15: Antisense Rna, Clinical Trial, Lead Compound
28 May 2016
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Document Summary
Dna or rna molecules that can form specific double-stranded couples with hiv rna. They can bind to hiv rna and prevent it from functioning in the infected cells and are being explored as therapeutics for hiv infection. Trials of drugs, vaccines, or therapies in humans. They are the final tests used before the treatments are approved for public use. A compound in drug development that shows activity against hiv in a laboratory culture. It may be modified by a pharmaceutical chemist to make even more effective antiviral compounds, some of which may eventually be useful in management of hiv infection in people. Some lentiviruses infect other species, including monkeys, sheep, and cats. The first clinical trials carried out during development of a drug or a treatment. Phase i clinical trials test for toxicity, and they establish the methods for achieving effective doses of the drug or treatment. Limited clinical trials that test for efficacy of the drug or treatment.
