BIO SCI 45 Lecture Notes - Lecture 2: Natural Killer Cell, Complement System, Dendritic Cell

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Must understand how hiv infects and causes disease to know how to prevent infection and slow progression of disease. Hiv impairs the ability of the immune system to defend against pathogens. Modern pharmacological/medicine: antibiotics inhibit growth of bacteria after infection and limits the disease, antivirals kill viruses. But drugs against many pathogens have not been identified. The immune system evolved by successful protection of the host from pathogens -> the infected" individual overcomes the toxicity" and lives/survives. Vaccines artificially stimulate the immune system to protect against infectious bacteria and viruses so that a person resists infection even if exposed to the agent. The immune system also: attacks cancer cells, eliminate toxins. Protein molecules: humoral (in fluids, ex. Plasma: antibody* = immunoglobulin (igg, igm, etc. ) *specifically recognizes and binds to a particular pathogen, tagging it for elimination: complement proteins bind to pathogens (more avidly if antibody is on the pathogen) and triggers killing of the pathogen.

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