BIO SCI 99 Lecture Notes - Lecture 1: Peptidyl Transferase, Glycosidic Bond, Pentose

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Office hours are held after lecture (tuesdays and thursdays) Goals: state central dogma and why the exceptions mentioned go against it. Understand why these differences favor dna as our genomic info. Be able to list the characteristics of the dna double helix and why they contribute to dna being our genetic info. Information can transfer from dna to dna in replication. Dna can be transferred to rna in transcription. Information can be transferred from rna to protein in translation. Using rna as a template can multiply into more rna, which is why viruses use rna - viruses use. Peptidyl transferase - an enzyme made of rna. Prions - proteins that are caused of mad cow disease. They do have the normal function in the cells, but the structure changes into a beta sheet structure - becomes dangerous - causes the development of mad cow disease. Flow of info is from protein to protein (an exception of central dogma)