MCB 2004C Lecture Notes - Lecture 27: Non-Gonococcal Urethritis, Chancre, Prevotella
Document Summary
Indigenous microflora near opening (meatus) of urethra, in distal urethra. Nonspecific urethritis (nsu) or nongonococcal urethritis (ngu) Enterococcus, neisseria, clostridium, actinomyces, prevotella, diphtheroids, enteric bacilli, candida. Herpes simplex type 2, sometimes type 1. Recurrent infection: vulva, perineal skin, legs, buttocks. Itching, tingling, soreness; redness followed by small, painful blisters. Transmission: direct sexual contact, in utero, at birth. Genotypes 16, 18 associated with cervical cancer. Small, moist, pink or red swellings; rapid growth, stalk development, rough surfaces. Females: vulva, vaginal wall, cervix, perivaginal skin, anus, rectum. Mucopurulent urethral discharge, urethral itching, burning on urination. Females: endocervical, urethral infections; infertility, chronic pelvic pain, pre-term delivery. Small genome 1mb harbors about 1000 genes. More than 1million cases of chlamydia reported last year (cdc) (sets std record: beats gonorrhea & syphilis) According to a 2005 study 5. 8% of ucf students tested positive. Cervicitis, bartholinitis, pid, salpingitis (pid), endometritis, vulvovaginitis. Disseminated gonococcal infection myalgia, arthralgia, polyarthritis, dermatitis. Still require treatment to avoid secondary syphilis.
