MCD BIO 104AL Lecture Notes - Lecture 2: Dna-Binding Domain, Gene Duplication
19 Jan 2020
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Whenever you do a database search, it"s important to know that the data is a good as what is in the database. It"s important to look through the entire list and find patterns within the material. Sometimes data might be based on the amount of information they had. Had to take sequence and create amino acid sequence. When they say six frames, they are rereading frames on both strands. If the proteins correlate, the genes are important. A transcription must have a dna binding domain in order to match up. Try to use info and put it together. If there is an evolutionary analysis and the tree reflects the analogy, then you are confident that the species is known. Nodes: two species last shared a common ancestor before divergence. Deuterostomes: the anus forms first, mouth forms second. Orthologs: homologs arrived through speciation (have the same number) Paralogs: homologs arrived through gene duplication (have different numbers)
