PHYSCI 121 Lecture Notes - Lecture 24: Flow Cytometry, Micrograph, Lesion
Document Summary
Even in areas with healthy looking muscle fibers. Not contractile tissue and inhibits the range of motions, the muscle begins to shorten in dmd patients. Inflammation in muscle repair has to occur in a certain order in time that destroys muscle and promotes repair. In different parts of the muscle at different times, or: asynchronously. The adjacent lesions undergo the sequence of repair at different times and the proper order and timing of inflammatory mediators is disrupted. Evidence for altered inflammatory response in areas between two asynchronous lesions. Two points of damage on the muscle created on the same day. Looked at the area in between the two points of damage. Some of the immune cells are marked in green. Micrograph shows ingrain cells between lesion one and 2. Another experiment: lesion 1 was created, and five days later lesion 2 was created. what you see is more immune cells compared to if both makrs came on the same day.
