BIOL 1107 Lecture Notes - Lecture 11: Tumor Suppressor Gene, Protein Kinase, P53

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26 Sep 2016
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Meiosis-promoting factor is present in the cytoplasm of m-phase cells and induces mitosis in all eukaryotes. Is a complex, not just composed of one molecule. Mpf is composed of two distinct subunits: a protein kinase and 2. cyclin. The protein kinase is an enzyme that catalyzes the transfer of a phosphate group from. The cyclin subunit subunit functions as a regulatory protein. Enzymatic cascade: one enzyme phosphorylates one enzyme which phosphorylates another enzyme and so on. Innate immune response, causing your body to raise your temperature, (by elevating heart rate, blood pressure) are aided by cyclins. The concentration of mpf cyclin increases during interphase, then peaks in m phase before decreasing again. If you cannot reach a certain concentration of mpf cyclin**** The mpf protein kinase is a cyclin-dependent kinase (cdk) is active only when bound to the cyclin subunits thus when cyclin concentration are high more mpf is active and the target proteins are phosphorylated.

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