NURS 3110 Lecture 7: Lecture 7

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7 Feb 2017
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Gram Positive Bacilli (Rods) Class 6
Gram positive spore forming
Objectives
Identify the morphology (i.e. spore-forming, etc) and virulence factors.
Identify key modes of transmission and associated approaches to prevention.
Contrast different strains and symptoms associated with infection.
Describe key treatment modalities.
Identify diagnostic tools in organism identification.
Organisms
Bacillus anthracis (anthrax)
o Not a major concern in the US
o Agent of biological warfare
o Be careful with imported goods
o If skin is exposed, there can be a localized infection
Necrotic ulcer
Clostridium perfringens
o Will be in clinical setting
o Vascular flow problems
Diabetics lack blood flow and oxygen delivery
o Especially anaerobic organisms have a problem
o Spore and vegetative mix
Anaerobic exposed to oxygen turn into spores
Especially if you take it out of the host
Clostridium tetani
o Spermy looking
Bacillus (Sporeforming)
Bacillus anthracis (anthrax)
o Pathogenesis
Primarily disease of animals, humans rarely affected
Zoonosis
Spores enter via injured skin or mucosa
Necrotic ulcer with edema
Inhalation: wool sorters disease hemorrhagic pneumonia
Induces bleeding
Anthrax toxin
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