NURS 3110 Lecture 7: Lecture 7

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Identify the morphology (i. e. spore-forming, etc) and virulence factors. Identify key modes of transmission and associated approaches to prevention. Contrast different strains and symptoms associated with infection. Bacillus anthracis (anthrax: not a major concern in the us, agent of biological warfare, be careful with imported goods, if skin is exposed, there can be a localized infection. Clostridium perfringens: will be in clinical setting, vascular flow problems. Diabetics lack blood flow and oxygen delivery: especially anaerobic organisms have a problem, spore and vegetative mix. Anaerobic exposed to oxygen turn into spores. Especially if you take it out of the host. Primarily disease of animals, humans rarely affected. Spores enter via injured skin or mucosa. Exotoxin can be problematic: cause thrombosis, cardiovascular shock, high mortality rate especially in lungs. X-ray shows mediastinal widening: specimens: fluids, pus from lesions, sputum, blood, treatment / control. Treat with penicillin, tetracycline, ciprofloxacin - give early. Prevent by vaccinating, dispose of animal carcass properly.

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