PNB 2265 Lecture Notes - Lecture 1: Cotai, Hemoglobin, Antibody
27 Jan 2017
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Composition: plasma (liquid, cells (white/red blood cells, cell fragments (platelets) Physical properties: mostly water (plasma, neutral ph (7. 4) Volume: men: 5-6 l (larger stature, women: 4-5 l. Transport: nutrients, wastes, gases (o2, co2) Regulation (kept relatively constant: ph (about 7. 4, osmolarity, temperature (about 38 c, fluid loss (injury) Helps to transport substances not normally soluble in blood: lipophilic hormones, lipids, hormones, steroids. Formed elements (37-54%: cells (rbc, wbc) Rbc (erythrocytes) are most abundant cell type in blood. Generally approximate about 50% plasma, 50% formed elements. Most blood samples are taken from the venous system because: easy to find, veins are thinner, low pressure so will seal quickly. Plasma expanders which are basically salt solution with lactate or carbohydrate added to maintain osmolarity are frequently given to help maintain blood pressure. Plasma expanders do not improve oxygen delivery. Packed rbcs take up % of tube (50ml out of 100ml tube, 50%)
