PNB 2265 Lecture Notes - Lecture 29: Aquaporin, Countercurrent Exchange, Collecting Duct System
10 Apr 2017
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The renal clearance of glucose should be _________ : greater than that of inulin, equal to the gfr, somewhat less than the gfr, zero, don"t want to excrete glucose, want to reabsorb it. The clearance rate for creatinine, a metabolite that is freely filtered and slightly secreted, can be used to provide a/an ___________ estimate of the gfr: exact, slight under, slight over, secretion adds materials for excretion. Water concentration: terrestrial animals generally need ways to conserve water, different animals have differing abilities to do this. Water permeability varies in different regions of renal tubule: the collecting ducts and late dcts permeability to water is regulated by adh. How urine is concentrated: medullary osmotic gradient , 300 in juxtamedullary, 1200 in medulla, collecting ducts can exploit this gradient to form a concentrated urine, osmotic gradient established by juxtamedullary nephrons and maintained by vasa recta.
