BILD 2 Lecture Notes - Lecture 3: Arteriosclerosis, Osmoregulation, Extracellular Fluid
17 Mar 2018
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Gas exchange, components of blood, volume, 8% of adult body weight, centrifuged blood reveals plasma (clear) & cells (red, plasma, 90% water, 3% electrolytes (nacl, kcl, ca2+, mg2+, etc. Same as interstitial fluid; important for nerve function: 7% proteins: immunoglobulins (antibodies), fibrinogens (clotting factors), Stiffening or hardening of artery walls: cholesterol forms plaques. Ldl: low density lipoproteins deposit cholesterol in plaques. Lipoproteins: proteins which carry lipids: carry cholesterol lipids from the liver to cells and tissue in the body where needed. In lung: o2 diffuses from alveolus to capillary; co2 from capillary to alveolus. 90% of protein in rbcs is hemoglobin (250,000,000 hb proteins per rbc): hb has 4 subunits. Carbonic anhydrase(a protein in blood) converts co2 to bicarbonate: co2 diffuses into rbc, and in another reaction, carbonic acid is formed, which dissociates in solution to hco3- bicarbonate. Bicarbonate solubility is higher than co2 solubility, so it is more easily transferred.
