BIMM 110 Lecture Notes - Lecture 3: Hmg-Coa Reductase, Diabetes Mellitus Type 1, Sterol Regulatory Element-Binding Protein
12 Sep 2015
School
Department
Course
Professor
Document Summary
In the us: place the following steps of the regulation of blood glucose levels in order. The first step has been labeled for you. __ binding of insulin to membrane receptors in adipocyte and muscle cells. __ glucose uptake is increased and stored as glycogen. __ exocytosis and activation of glucose transporters glut4. ___ glucose uptake via glut 2 transporters in pancreatic beta cells. ____ depolarization and calcium influx in beta cells. ___ pip2 is converted to pip3, binds pkb: a mouse is generated carrying a homozygous mutation in the pkb gene which leads to the inability of pkb to be phosphorylated. Would this lead to diabetes type 1 or 2: a man consumed some raw sushi that contained a toxin that desensitized his k+ channels (makes them insensitive to intracellular atp levels). After his sushi dinner, he enjoys a big piece of cake. After finishing his cake, he feels extremely thirsty and has trouble seeing clearly.
