ANFS332 Lecture Notes - Lecture 22: Cytotoxic T Cell, Intracellular Parasite, Adaptive Immune System
4 Feb 2020
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Document Summary
Parasitology, protozoa and helminths mechanisms of immunity. Viruses infected cells display fragments of viral antigens on the cell surface (antigen presentation). cytotoxic t cells destroy infected cells and antibodies neutralize viruses before they infect cells. Intracellular parasites cytotoxic t cell response (malaria) Combined immunodeficiency (cid) is a genetic disorder characterized by the complete inability of the adaptive immune system to mount an immune response. It is usually due to the absence of both t and b lymphocytes. Parasitic diseases have a huge impact on man and domestic animals. On a world-wide basis parasitic infections outrank cancer as the #1 killer in the world. 40% of the world population is at risk. Leading cause of morbidity in the developing world. Kills 4x more people/year than hiv but the global research budget is 15x less. Billions spent yearly on vaccines and chemotherapies. Some areas of the globe are unusable for certain agricultural practices because of parasites.
