BISC403 Lecture Notes - Lecture 15: Contact Inhibition, Autocrine Signalling, S Phase
25 Apr 2017
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Document Summary
One name, different diseases; many things with one name. Lost the ability to follow the normal control the body exerts on cells: escape the normal control mechanisms, continue to grow, malignant invades and spreads, very different in every person. Cancer is more bad luck than lifestyle or genes: random mutations could explain around 65% of cancer incidence, cancer cells are angry cells. Some causes: viruses or bacteria, in the process of incorporating into the genome, chemicals, radiation, heredity, diet, hormones. The relative percentages of new cancers in the u. s. that occur at different sites: 1/3 of females, of males will develop cancer in their lifetime. Cancer is not considered an inherited illness because most cases of cancer, perhaps. 80-90%, occur in people with no family history of the disease: inherited genetic alterations tend to increase an individual"s susceptibility to developing cancer in the future.
