BISC207 Lecture Notes - Lecture 10: Cytoplasmic Streaming, Autophagy, Christian De Duve
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BISC207 Full Course Notes
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Describe the structure and function of the endomembrane system and how it regulates protein trafficking- pulse chase experiments, lysosome and degradation. Chase has no radiolabel: recycling material in lysosomes, lysosomes also digest large structures and organelles in the cytoplasm. Portions of the cytoplasm, including damaged organelles, are enclosed to form autophagosomes. Fuses with lysosome for digestion: living dynamic and efficient systems in the cell, belgian scientist christian de duve was awarded nobel prize in physiology or. Transports materials within the cell whole: the dynamic cytoskeleton, the cytoskeleton. Is a dense and complex network of fibers: helps maintain cell shape by providing structural support. Is not a static structure like scaffolding used at construction sites: its fibrous proteins move and change to. Even move the cell itself: three types of cytoskeletal elements, microfilaments, double helix of actin monomers. Intermediate filaments: strong fiber composed of intermediate filament proteins, microtubules, hollow tube formed from tubulin dimers, two monomers.