HDFS472 Lecture Notes - Lecture 2: Biotransformation, Drug Interaction
10 Mar 2019
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Document Summary
Process of changing the molecular structure of a drug into forms that make it easier for the body to excrete. Accomplished chiefly by enzymes in the liver. By products/smaller products as result of biotransformation. For most drugs, rate of biotransformation increases as the dose taken increases. More than one drug at a time can cause reactions that affect biotransformation/allowing your body to excrete. Marijuana gets stored in fat cells in your body. When concentration in blood is not yet high enough to have a behavioral effect. Can be a matter of seconds or mor4e. Alcohol is small enough of a molecule that we don"t digest, but is quick. A drug that you smoke almost immediately hits brain. Drug interactions affect the behavioral impact of drugs. Two drugs in combination may produce an effect that is greater than the effect of either drug alone. Adding the effects of the two drugs together.
