KAAP220 Lecture Notes - Lecture 6: Melanoma, Hemidesmosome, Stratum Basale
5 Mar 2018
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Document Summary
Fundamentals of anatomy and physiology chapter 5. The integumentary system: skin and accessory structures, most accessible organ system, body"s first line of defense against environment, can be referred to as skin or integument, sixteen percent of total body weight, has two major components. 1. 5 2m2 in surface area: cutaneous membrane, accessory structures. Subcutaneous layer (hypodermis: not part of integument, separates integument from deep fascia. Epidermis: multiple layers of cells (strata) with different functions, primary cell type in epidermis is keratinocyte, deeper layers of epidermis form epidermal ridges, adjacent to dermal papillae (papilla; nipple-shaped mound) Fingerprints: pattern of dermal and epidermal ridges on surface of fingertips, unique pattern that does not change during lifetime. Thin skin: covers most of body surface, contains four strata (layers) Thick skin: found on palms of hands and soles of feet, contains five strata (layers) Lose water through insensible perspiration (unable to see or feel) and sensible perspiration (sweat)
