ANT 3520 Lecture Notes - Lecture 18: Congenital Syphilis, Endochondral Ossification, Vitamin D Deficiency

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Derived from paleopathology- studying skeletal remains from past cultures. Normal- tissue or organ functionally intact, free from disorder, capable of sustaining its function. Anomaly- deviates from norm, but is non lethal and does not significantly change function. Pathological- deviation from norm in a way that compromises tissue or organ. Not very common; only few diseases affect the skeleton. Reactions to disease are generalized and vary from person to person. When disease does affect the skeleton, doesn"t produce same effect all the time- requires ddx. Lytic lesion o: abnormal cell destruction (circular areas that lack density) New bone formed in response to injury to/stimulation of periosteum that surrounds the bone. Can be caused by tumors, drug reactions, infection, metabolic conditions. Bone can enlarge and form bone buttresses or sheaths(involucrum) , drainage channels for pus (cloacae) and islands of dead bone (sequestra) Skeletal involvement shows a fine balance between good and bad health. Vemereal treponemal infection; heart, brain and bones affected.

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