MICR 130 Lecture Notes - Lecture 4: Shiga Toxin, Tooth Enamel, Typhoid Fever

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Large intestine has the largest density of normal. Millions of bacteria per ml of saliva. Stomach and small intestine normally have fewer bacteria. Large intestine has a large number of bacteria. Teeth and gums can be colonized by bacteria that erode the tooth enamel and cause gums to recede. Teeth and gum can be colonized by bacteria that erode the tooth enamel and cause gums to recede. Streptococcus mutans binds to enamel and creates a biofilm that allows several other species to attach to teeth. Metabolism of sugars by bacteria in the biofilm leads to fermentation and lactic acid production. Sugarless sweeteners can not be metabolized by the bacteria so do not contribute to dental caries. If gums recede far enough, tooth loss can occur. Bacteria adhering to teeth cause inflammation of gums. Streptococcus mutans bind to enamel and create a biofilm that allow several other species to attach to teeth.

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