BIOL 4320 Lecture Notes - Lecture 8: Reverse Transcriptase, Chromosome, Retrovirus

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Transposon: transposable elements: jumping gene", a dna sequence able to insert itself a new location (mobile) simple translocation or generation of a new copy. Transposon is present in both prokaryotes and eukaryotes. Some transposons are not functional but they can be transposed with the help from a functional transposon. Retro element: transposable element that involves rna intermediate for transposition. Transposition does not rely on any relationship between the sequences at the donor and recipient sites. Roughly half of the human genome is composed of transposons. Each is element is different in sequence but share common features; autonomous units. An is is a transposon that codes for the enzyme(s) (i. e. , transposase) needed for transposition flanked by short inverted terminal repeats. The target site at which a transposon is inserted is duplicated during the insertion process to form two repeats in direct orientation at the ends of the transposon.

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