PSYC 3341 Lecture Notes - Lecture 5: Eric Kandel, Sensory Neuron, Motor Neuron

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Adaptive role of synapses in learning and memory: neuroplasticity, required for learning and memory, the nervous system"s potential for change, which enhances its ability to adapt, learning, relatively permanent change in behavior that results from experience. The hebbian synapse: a synapse becomes more effective because of simultaneous activity in the presynaptic and postsynaptic neurons, neurons that fire together wire together. Eric kandel and the aplysia californica: slug with about 20,000 neurons. Influx of ca2+ ions in response to an action potential decreases: less neurotransmitter released at the presynaptic membrane, less depolarization of the postsynaptic membrane. Sensitization: enhanced response to a stimulus, opposite of habituation, example: ptsd, exposure therapy is basically habituation, electric shock to the tail enhances the gill withdrawal response. Interneuron delivers message from tail sensory neuron to siphon sensory neuron via serotonin: action potential gets stronger. Influx of sodium: decreased k+ efflux potassium stays in the cell, super positive; doesn"t go back down, prolonged firing.

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