SOC 3382 Lecture Notes - Lecture 17: Basal Ganglia, Cerebral Cortex, Marihuana Tax Act Of 1937

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After smoking: t h c is absorbed rapidly by the blood and travels to the brain and then to the rest of the body, peak mood-altering and cardiovascular effects occur within 5 to 10 minutes. After oral administration: t h c is absorbed more slowly, peak effects occur about 60 to 90 minutes following ingestion. Metabolism: t h c has a half-life of 19 hours, complete elimination of t h c and its metabolites may take 2 to 3 weeks. T h c increases heart rate in a dose-dependent fashion: time course differs depending on route of administration. Pulmonary effects: acute, chronic, few effects on breathing. Heavy marijuana smoking over a long period could lead to clinically significant impairment of pulmonary function. Self-administration: studies show young adults self-administer smoked marijuana and oral t h c. Under controlled laboratory conditions, participants prefer: marijuana cigarettes with higher t h c content, more oral t h c during periods of social interaction.

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