SOC 3382 Lecture Notes - Lecture 12: Lethal Dose, Psychoactive Drug

• School: University of Houston
• Department: Sociology
• Course: SOC 3382
• Professor: Graves

Document Summary

Dose-response curve: graph depicting the relationship between a range of drug doses and the resulting drug effects. Threshold the lowest dose at which an effect is observed. Different dose-response curves can be created for different drug effects: some response systems have higher thresholds, some drugs have an all-or-none dose-response relationship. Figure 5. 2: relationship between alcohol dose and multiple responses. Safety margin: difference between the dose that produces the desired therapeutic effect in most patients and the lowest dose that produces an unacceptable toxic reaction. Potency: amount of a drug required to produce a particular effect. Side effects: unintended effects that accompany therapeutic effects. Effective dose: dose of a drug that produces a meaningful effect in some percentage of test subjects, e d50 is the effective dose for half the animals in a drug test. Lethal dose: dose of a drug that has a lethal effect in some percentage of test subjects.