PHYS 1302 Lecture Notes - Lecture 4: Pressure Gradient, Organic Anion-Transporting Polypeptide, Macula Densa
Document Summary
Kidneys are responsible for the homeostatic regulation of water/ion content of blood (fluid and electrolyte balance) If ecf is too acidic, kidneys remove h+ and conserve bicarbonate (hco3-) ions which act as a buffer. If ecf is too alkaline, kidneys remove hco3- and conserve h: excretion of wastes, kidneys remove metabolic waste (urea, uric acid, and creatinine, production of hormones, synthesis of epo i. Epo regulates rbc synthesis: release of renin i. Regulates production of hormones involved in na+ balance: renal enzymes help convert vitamin d into hormone that regulates. Urinary system consists of kidneys, ureters, bladder, and urethra. Urine production begins when water and solutes move from plasma into hollow tubules (nephrons) that make up most of the kidneys. Nephrons modify composition of fluid as it passes through. Modified fluid (urine) leaves kidney and passes into hollow tube (ureter) 2 ureters one leading from each kidney to urinary bladder.
