MCB 150 Lecture Notes - Lecture 4: Ionic Bonding, Keratin, Ferritin

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Topic 4 - proteins: amino acids and protein folding. We are the product of our proteins and protein activity. The study of proteins and protein activity: proteomics. Proteins account for most of the dry weight in the cell. More than half of the macromolecules in a typical cell. Proteins are involved in nearly all types of cell functions: R group: side chain: differs from one to one. Incoming amino acid: give up h in amino group. Existing protein/amino acid: give up oh- group in carboxyl group. Create covalent bond - peptide linkage (peptide bond) Join the next amino acid in n c direction. A long chain of amino acids = polypeptide. A polypeptide with a purpose = protein. 20 different amino acids differ only in r groups distinct properties to that amino acid. Large number of amino acids makes possible a huge number of different amino acid sequences. Polypeptide modification biological purposes protein.

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