MCB 150 Lecture Notes - Lecture 23: Osmoregulation, Signal Peptide, Autophagosome

• School: University of Illinois
• Department: Molecular and Cell Biology
• Course: MCB 150
• Professor: B Mehrtens

Document Summary

Lysosomes trash compartment degrade something big. Appeared dark materials degrade macromolecules lysosomal acid hydrolases enzymes hydrolyzing covalent bond under acidic condition (5) inactive if floating around in cytoplasm. Create acidic ph environment proton pump atp- dependent proton pump maintain ph~5. Lysosome will eventually degrade themselves after running out of work. Extra shield of carbohydrates keep busy before degradation. Part 1: vesicular traffic to and from an early endosome: Creating new lysosome maturation from endosomes . Liver cells need to have insulin receptor molecule) Blue beads outside as signaling molecules degrade blue beads into individual amino acid lysosomes have transport channels export of monomers once the macromolecules has been digested. Endocytosis budding from outside of the cell. Early endosome collection of endocytic vesicle membrane bound organelle, irregular in shape always materials fuse/bud off with it. Already have a proton pump does not have any hydrolase has the ability to separate what need to be degraded/recycle. Recycle fuse with recycling endosome+bud off.