MCB 150 Lecture Notes - Lecture 29: Glycoprotein, Endosome, Dna Virus

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Have been found in all three domains. Obligate intracellular parasites dependent on host cells must be inside the cell to get the work done obligate to use host machinery. Can persist on their own under permissive conditions do not die can only become not infectious. Can reproduce only within a host cell + using tools from host. Genomes may code for a few enzymes or proteins, but they must use atp, Aas, trna, nucleotides, ribosomes, etc. from host to replicate. Do not perform glycolysis no atp. Simple structures nucleic acid, protein coat (capsid) sometimes a few enzymes. Some animal viruses are surrounded by a lipid/protein membrane acquired during release from host cell enveloped virus. Icosahedral 20 sided shape (with or without a tail) Can be either single- or double-stranded (both dna and rna) Can be single copy or multiple copies. Can be intact (all coding regions on one pieces of nucleic acid) or segmented.

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