NURS 245 Lecture Notes - Lecture 6: Helicobacter Pylori, Human Microbiota, Immunogenicity
Document Summary
Host-we are a super organism or an ecosystem of mutually dependent life forms. Normal flora-20 million/ square inch: outnumber our cells 10:1 a) Sites-skin, moist area (mucus membranes), mouth, occasionally areas of stomach/lower gi tract b) c) Commensalism-you and the organism live side by side, the organism benefits from living with you-you are a protective environment for them. Helicobacter pylori protects against esophageal reflux-but can lead to problems in the stomach. Opportunists-when normal flora cause problems what kind of problems do they cause and where do they cause them. It takes opportunities to multiply rapidly and then cause harm a) Staph sites: normal flora of skin-skin and wound infections, toxic shock syndrome via vaginal membrane, endo-carditis, pneumonia, food poisoning, septic arthritis (1) Resistant staph strains develop as both normal flora and opportunists due to staph being treated with antibiotics b) Strept sites: normal flora of upper respiratory tract-upper respiratory tract, middle ear, pneumonia c)
