ANIMLSCI 332 Lecture Notes - Dicoumarol, Fibrin, Melilotus
29 Apr 2014
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Found in green leafy vegetables; very little in fruits and grains. Meats and dairy products have low to moderate levels of vit k. Microbial synthesis in the rumen / intestine (with animals that practice coprophagy) seems to be the most significant in most animal species. Vitamin k synthesized by microbial populations of the rumen and lower gi (obtained by coprophagy in monogastrics). Absorption depends upon the form of the vitamin . Phylloquinone can be absorbed by an energy dependant process in the si. Menaquinones and menadione absorbed via passive diffusion in the distal part of the small intestine as well as the colon! After absorption into the imc vit k is incorporated into the chylomicron where it is transported to the liver (as part of the chylomicron remnant) and exported as part of the. Menadione is rapidly metabolized and excreted in the urine. Catabolized phylloquinone and menaquinones are excreted in the feces via bile.
