MICROBIO 140P Lecture Notes - Lecture 12: Mononegavirales, Chlorocebus, Filoviridae
20 Mar 2016
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Ebola: you get sick and in a matter of days you"re dead. The story starts: marburg germany: 1967-> marburg virus: never heard of before. 31 cases, 7 deaths traced back to belgian colonial africa. What is now the democratic republic of congo. These monkeys were used to develop vaccines. Some were infected with marburg virus and doctors working with them got infected, went back to germany, and died. Viruses: not eukaryotic or prokaryotic, singular, but not cellular, they lack the ability to make their own copies. They do have the information though: viruses use their neuraminidase (like an outer velcro shell) and lach onto a cell to use the cell"s abilities to reproduce the virus. They hijack the cell: viruses mutate 10,000 times faster than we can. Different viruses: dna viruses, rna viruses: retroviruses: take rna, make dna and put it in the cell to make more viruses.
